Effects of acetazolamide on linear growth in children with pseudotumor cerebri syndrome
نویسندگان
چکیده
Background/introduction While oral acetazolamide is a cornerstone of management adult and pediatric PTCS, previous studies have suggested that used in children with other conditions may influence growth. Aims methods Retrospective chart review involving single tertiary medical center. Thirty-four definite or probable PTCS were identified. Analysis was restricted to individuals from whom anthropometric data available before during treatment (n=22). Results Half (n=11/22) showed decline BMI Z-scores. Sixty-three percent (n=14/22) decrease height Z-scores acetazolamide; 6 these 14 who had complete data, 3 at least partial recovery after discontinuation acetazolamide. Conclusion Acetazolamide be associated growth suppression some treated for PTCS. In cases, the appears reverse once stopped.
منابع مشابه
Brain Imaging in Pediatric Pseudotumor Cerebri Syndrome
Pseudotumor cerebri syndrome (PTCS) is an umbrella term used for the constellation of symptoms caused by increased intracranial pressure (ICP) without hydrocephalus, spaceoccupying lesion, or anomalies of brain parenchyma and with a normal cerebrospinal fluid (CSF) composition.1 PTCS has a reported incidence of 0.9 per 100,000 in the general population, but it rises to 19 per 100,000 in obese w...
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ژورنال
عنوان ژورنال: Frontiers in ophthalmology
سال: 2023
ISSN: ['2768-4121']
DOI: https://doi.org/10.3389/fopht.2022.1042529